Department of Anesthesiology & Perioperative Care: School of Medicine: University of California, Irvine

Areas of Interest

Peter Breen, MD photo

Peter H. Breen, MD, FRCPC

Assistant Professor

Dr. Breen investigates Gas Kinetics and Metabolism During Non-Steady State in Anesthesia, including non-steady-state carbon dioxide kinetics and the more general gas kinetics in anesthesia during non-steady state. His studies explored and tested hypotheses of gas exchange, metabolism, and the state of “tissue wellness” during non-steady-state conditions in anesthesia and critical care medicine. Experiments included bench simulations, computer modeling, and clinical studies. These studies stimulated collaborations and consultations with Information and Computer Science, Pulmonary and Critical Care Medicine, and the Department of Mathematics. Other areas of Dr. Breen’s research programs include the study of the pathophysiology and treatment of combined carbon monoxide and cyanide poisoning and studies of respiratory mechanics.

Selected Publications

  1. Abraham Rosenbaum and Peter H. Breen Importance and Interpretation of Fast-Response Airway Hygrometry During Ventilation of Anesthetized Patients Journal of Clinical Monitoring and Computing Volume 21, Number 3, 137-146, DOI: 10.1007/s10877-006-9065-5
  2. Christian Koch, MD, Christine Hollister, MD and Peter H. Breen, MD, FRCPC Infusion Pump Delivers Over-Dosage of Propofol as a Result of Missing Syringe Support Anesthesia & Analgesia April 2006 vol. 102 no. 4 1154-1156
  3. Abraham Rosenbaum, MD, Heike C. Howard, MS and Peter H. Breen, MD, FRCPC Novel Portable Device Measures Preoperative Patient Metabolic Gas Exchange Anesthesia & Analgesia February 2008 vol. 106 no. 2 509-516
  4. Abraham Rosenbaum, Christopher W. Kirby and Peter H. Breen Bymixer system can measure O2 uptake and CO2 elimination in the anesthesia circle circuit Canadian Journal of Anesthesia / Journal canadien d'anesthésie Volume 54, Number 6, 430-440
  5. Peter H. Breen How do changes in exhaled CO2 measure changes in cardiac output? A numerical analysis model Journal of Clinical Monitoring and Computing Volume 24, Number 6, 413-419

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